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(Senior) Research Associate, In Vivo Pharmacology
Full Time
Boston, Massachusetts, United States
Job description
Scismic is supporting the growth of a biotech company based out of Allston, MA!
We are seeking a highly-motivated In Vivo Pharmacology Research Associate/Senior Research Associate who thrives in a fast-paced and creative environment to push the capabilities of our multiplexed in vivo drug discovery platform. Together with senior researchers, you will play a critical role in executing in vivo studies to support internal research projects. This is a hands-on role and you should have extensive experience in multiple aspects of in vivo pharmacology including dosing, pharmacokinetic sampling, and necropsy, among others. The ideal candidate must be able to work effectively both in a collaborative setting and independently.
We are seeking a highly-motivated In Vivo Pharmacology Research Associate/Senior Research Associate who thrives in a fast-paced and creative environment to push the capabilities of our multiplexed in vivo drug discovery platform. Together with senior researchers, you will play a critical role in executing in vivo studies to support internal research projects. This is a hands-on role and you should have extensive experience in multiple aspects of in vivo pharmacology including dosing, pharmacokinetic sampling, and necropsy, among others. The ideal candidate must be able to work effectively both in a collaborative setting and independently.
Responsibilities:
- Small animal handling and dosing of test agents via various routes (IV, SC, IP, PO).
- Collect body weight, tumor volume measurements via calipers and clinical observation data.
- Perform tissue and tumor sample collection from in vivo experiments.
- Perform blood collections via submandibular cheek bleeds and cardiac punctures.
- Cell culture and tissue homogenization.
- Assist in maintaining inventories.
- Maintain accurate and organized data entry and analysis.
- Communicate to the team via technical reports and oral presentations.
Required Qualifications:
- Bachelors or Masters and 1-2+ years of experience (biotech/pharma industry preferred) in executing in vivo proof of concept and efficacy experiments in mice.
- Demonstrated expertise in in vivo study execution.
- Collaborative, curious, and flexible with strong communication skills, both written and oral,
- Self-motivated, highly organized, able to work independently with minimal supervision, and able to multitask.
- Strong attention to detail.
- A genuine passion for science and developing medicines. Preferred Qualifications
- Experience in bioanalytical assays for protein therapeutics (PCR, nucleic acid extraction, ELISA, Western Blot, etc)..
- Experience writing detailed research project plans and methodological SOPs that guide yours and other team members’ laboratory activities.
- Experience in tissue sectioning, histology and microscopy is a plus.
- Experience in mouse health monitoring is highly preferred.
- Skilled with Microsoft Office, GraphPad Prism, and ImageJ.
- Driving license and reliable vehicle is a must.